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Antihypertensives -Thiazide and related diuretics
Definition Poisoning from a thiazide or related diuretic.
Alternative Names 
Poisonous Ingredient any of the following
  • bendroflumethiazide
  • benzthiazide
  • chlorothiazide
  • chlorthalidone
  • hydrochlorothiazide (HCTZ)
  • hydroflumethiazide
  • indapamide
  • methyclothiazide
  • metolazone
  • polythiazide
  • quinethazone
  • trichlormethiazide
  • Note: This list may not be all inclusive.
    Where Found
  • bendroflumethiazide (Naturetin)
  • benzthiazide (Exna)
  • chlorothiazide (Diuril, Diurigen)
  • chlorthalidone (Thalitone, Hygroton
  • hydrochlorothiazide (Esidrix, HydroDIURIL, Hydro-Par, Oretic)
  • hydroflumethiazide (Diucardin, Saluron)
  • indapamide (Lozol)
  • methyclothiazide (Enduron, Aquatensen)
  • metolazone (Zaroxolyn, Diulo)
  • polythiazide (Renese)
  • quinethazone (Hydromox)
  • trichlormethiazide (Metahydrin, Naqua, Diurese)
  • Note: This list may not be all inclusive.
  • body as a whole
  • dizziness
  • drowsiness
  • fainting
  • confusion
  • weakness
  • coma
  • muscle cramps
  • frequent urination
  • pale
  • colored urine
  • fever
  • respiratory
  • slow respirations
  • eyes, ears, nose, and throat
  • photosensitivity
  • color vision abnormalities (yellow tinge)
  • skin
  • rash
  • yellow skin
  • gastrointestinal
  • nausea and/or vomiting
  • heart and blood vessels
  • low blood pressure
  • Home Treatment
  • Do not induce
  • emesis ( vomiting ) unless instructed to do so by Poison Control or by a physician. If instructed to induce emesis, proceed as follows or as otherwise instructed: Give the usual dose of ipecac syrup: 15 milliliters (ml) or 1 TABLEspoonful for children and 30 ml (2 TABLEspoonsful) for an adult. Follow with 1/2 glass or 4 ounces (oz.) of water for children or 8 to 12 oz. of water for adults. Repeat 1 more time in 1/2 hour if emesis has not occurred.
    Before Calling Emergency Determine the following information:
  • the patient's age, weight, and condition
  • the name of the product (ingredients and strengths if known)
  • the time it was swallowed
  • the amount swallowed
  • Poison Control, or a local emergency number They will instruct you if it is necessary to take the patient to the hospital. See Poison Control centers for telephone numbers and addresses. Take the container with you to the emergency room.
    What to expect at the emergency room Some or all of the following procedures may be performed:
  • induce
  • emesis
  • administer activated charcoal
  • monitor
  • vital signs ( blood pressure , pulse , and so forth)
  • monitor
  • EKG (monitors heart function)
  • blood samples drawn to determine serum
  • electrolyte levels
  • correction of
  • electrolyte imbalances and fluid imbalances
    Expectations (prognosis) Patients usually respond well to treatment. Serious symptoms and death are unlikely.

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