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Health Encylopedia

 
Albumin
 
SubjectContents
Definition A test that measures the amount of albumin in serum.
Alternative Names 
How the test is performed Blood is drawn from a vein ( venipuncture ) or capillary. The laboratory centrifuges the blood to separate the cells from the serum. The albumin test is done on the serum.
How to prepare for the test The health care provider will advise you, if necessary, to discontinue drugs that may affect the test. Drugs that can increase albumin measurements include anabolic steroids, androgens, growth hormone , and insulin.
How the test will feel 
Why the test is performed This test helps in determining if a patient has liver disease or kidney disease , or if not enough protein is being absorbed by the body. Albumin is the protein of the highest concentration in plasma. Albumin transports many small molecules in the blood (for example, bilirubin , calcium, progesterone, and drugs). It is also of prime importance in maintaining the oncotic pressure of the blood (that is, keeping the fluid from leaking out into the tissues). This is because, unlike small molecules such as sodium and chloride, the concentration of albumin in the blood is much greater than it is in the extracellular fluid. Because albumin is synthesized by the liver, decreased serum albumin may result from liver disease. It can also result from kidney disease, which allows albumin to escape into the urine. Decreased albumin may also be explained by malnutrition or a low protein diet.
Normal Values The normal range is 3.4 to 5.4 gm/dl. Note: gm/dl = grams per deciliter Normal values may vary slightly from laboratory to laboratory.
What abnormal results mean Lower-than-normal levels of albumin may indicate:
  • ascites
  • burns
  • (extensive)
  • glomerulonephritis
  • liver disease
  • (for example,
  • hepatitis , cirrhosis , or hepatocellular necrosis "tissue death")
  • malabsorption
  • syndromes (for example,
  • Crohn's disease , sprue , or Whipple's disease )
  • malnutrition
  • nephrotic syndrome
  • Additional conditions under which the test may be performed:
  • diabetic nephropathy/sclerosis
  • hepatic encephalopathy
  • hepatorenal syndrome
  • membranous nephropathy
  • tropical sprue
  • Wilson's disease
  • What the risks are 
    Special considerations
  • If you are receiving large amounts of
  • intravenous fluids, the results of this test may be inaccurate. Albumin will be decreased during pregnancy.
      

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