| Subject | Contents |
| Definition | Poliomyelitis is a disorder caused by a viral infection (poliovirus) that can affect the whole body, including muscles and nerves. Severe cases may cause permanent paralysis or death.
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| Alternative Names | Polio; Infantile paralysis |
| Causes, incidence, and risk factors | Poliomyelitis is a communicable disease caused by infection with the poliovirus. Transmission of the virus occurs by direct person-to-person contact, by contact with infected secretions from the nose or mouth, or by contact with infected feces. The virus enters through the mouth and nose, multiplies in the throat and intestinal tract, and then is absorbed and spread through the blood and lymph system . Incubation ranges from 5 to 35 days (average 7 to 14 days). Risks include: lack of immunization against polio travel to an area that has experienced a polio outbreak pregnancy ; very old or very young age trauma to the mouth/nose/throat, such as recent tonsillectomy or dental surgery unusual stress or physical exertion after an exposure to poliovirus (emotional and physical stress can weaken the immune system) Polio occurs worldwide. However, no cases of polio have been reported in the United States in recent years. (The last case of non-vaccine related polio acquired in the United States was in 1979.) There have been very few cases in the Western hemisphere. It once affected mostly infants and children, but now is mostly seen in people over 15 years old. It is more common in the summer and fall. Adults and young girls are more likely to be infected, but infection in young boys is more likely to result in paralysis . Between 1840 and the 1950s, polio was a worldwide epidemic. Since the development of polio vaccines, the incidence is much reduced. Outbreaks still occur, usually in non-immunized groups. |
| Symptoms | There are three basic patterns of polio infection: subclinical infections, nonparalytic, and paralytic. Approximately 95% of these are subclinical infections, which may go unnoticed. Clinical poliomyelitis affects the central nervous system (brain and spinal cord) and is divided into nonparalytic and paralytic forms. It may occur after recovery from a subclinical infection. SUBCLINICAL INFECTION no symptoms, or symptoms lasting 72 hours or less slight feverheadache general discomfort or uneasiness ( malaise )sore throat red throat vomiting NONPARALYTIC POLIOMYELITIS symptoms last 1 to 2 weeks moderate fever headache stiff neck vomiting diarrheaexcessive tiredness , fatigue irritability pain or stiffness of the back, arms, legs, abdomen muscle tenderness and spasm in any area of the body neck pain pain front part of neck neck stiffnessback pain or backacheleg pain (calf muscles) skin rash or lesion with pain muscle stiffness PARALYTIC POLIOMYELITISfever , occurring 5 to 7 days before other symptoms headache stiff neck and back muscle weakness , asymmetrical
rapid onset progresses to paralysis location depends on where the spinal cord is affected abnormal sensations (but not loss of sensation ) of an area sensitivity to touch, mild touch may be painful difficulty beginning to urinateconstipationbloated feeling of abdomen swallowing difficultymuscle painmuscle contractions or muscle spasms , particularly in the calf, neck, or backdroolingbreathing difficulty irritability or poor temper control positive Babinski's reflex |
| Signs and tests | Examination may shows signs of meningeal irritation (similar to meningitis ), such as stiff neck or back stiffness with resistance to neck flexion. When sitting, the person may need to support the body with the arms. The person may have difficulty lifting the head or lifting the legs from a supine position (lying flat, face up). Reflexes may be abnormal. The disorder may resemble encephalitis , and it may affect the cranial nerves and cause difficulty with facial expression, swallowing, chewing, and so on. It may also cause choking or difficulty breathing . Viral cultures of throat washings, stools, or cerebrospinal fluid (CSF) confirm the diagnosis (see CSF collection ). Routine CSF examination may be normal or show slight increase in pressure, protein , and white blood cells. |
| Treatment | The goal of treatment is to control symptoms while the infection runs its course. Lifesaving measures, particularly assistance with breathing, may be necessary in severe cases. Symptoms are treated according to their presence and severity. Antibiotics may be used to treat urinary tract infections . Medications, such as bethanechol, may reduce urinary retention. Analgesics are used to reduce headache , muscle pain '>muscle pain , and spasms . Narcotics are not usually given because they increase the risk of breathing difficulty . Moist heat (heating pads, warm towels, etc.) may reduce muscle pain '>muscle pain and spasm. Activity is limited only by the extent of discomfort and the extent of muscle weakness '>muscle weakness . Physical therapy, braces or corrective shoes, orthopedic surgery, or similar interventions may eventually be necessary to maximize recovery of muscle strength and function. |
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| Expectations (prognosis) | The outcome varies with the form (subclinical, nonparalytic, or paralytic) and the site affected. If the spinal cord and brain are not affected, which occurs in over 90% of cases, complete recovery is likely. Brain or spinal cord involvement is a medical emergency that may result in paralysis or death (usually from respiratory difficulties). Disability is more common than death. Lesions high in the spinal cord or in the brain are associated with greater risk for respiratory difficulty. |
| Complications | spread of infection to other non-immunized persons permanent muscle paralysis , disability, deformitypulmonary edemashock complications of immobility and respiratory (lung) involvementaspiration pneumoniahypertensionurinary tract infectionskidney stonesparalytic ileus (loss of intestinal functioning) myocarditiscor pulmonale |
| Calling your health care provider | Call your health care provider if symptoms of poliomyelitis occur. Call your health care provider if someone close to you has developed poliomyelitis and you are not immunized against the disorder. Call your health care provider if your child's polio immunization (vaccine) is not up-to-date. |
| Prevention | Polio immunization (vaccine) effectively prevents poliomyelitis in most persons (immunization is over 90% effective). |
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