| Subject | Contents |
| Definition | An absence of a natural substance normally present in the stomach and essential to the digestion of vitamin B-12 . Lack of intrinsic factor leads to pernicious anemia and vitamin B-12 deficiency. Congenital lack of intrinsic factor causes inadequate absorption of vitamin B-12 starting around 6 months of age, while the juvenile type tends to manifest itself at an age greater than 10 years. There is an autosomal recessive inheritance pattern suggested in the congenital form. |
| Alternative Names | Addisonian (juvenile) lack of intrinsic factor; Congenital lack of intrinsic factor |
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