| Subject | Contents |
| Definition | A multifactorial inherited disorder that affects the way bilirubin is processed by the liver and causes jaundice . |
| Alternative Names | Icterus intermittens juvenilis; Low-grade chronic hyperbilirubinemia; Familial non-hemolytic - non-obstructive jaundice; Constitutional liver dysfunction; Unconjugated benign bilirubinemia |
| Causes, incidence, and risk factors | Gilbert's disease is common, affecting up to 10% of some Caucasian populations. The most significant symptom of this condition is jaundice . Affected individuals usually have no jaundice. However, jaundice appears under conditions of exertion, stress , fasting, and infections. The condition is usually benign . |
| Symptoms | mild jaundicefatigue Note: There may be no symptoms. |
| Signs and tests | A serial serum indirect bilirubin shows changes consistent with Gilbert's disease. |
| Treatment | Usually no treatment is necessary. The focus should be on the underlying condition resulting in the stress. |
| Support Groups | |
| Expectations (prognosis) | Jaundice may fluctuate and persist throughout the patients life but usually causes no health problems. |
| Complications | There are usually no complications. |
| Calling your health care provider | Call your health care provider if you have jaundice or persistent abdominal pain . |
| Prevention | This is an inherited disorder; there is no proven prevention. |
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